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Chronic obstructive pulmonary disease is a preventable and treatable disease characterized by airflow limitation that is not fully reversible. The airflow limitation is usually progressive and characterized by a mixture of small airway disease (obstructive bronchiolitis) and parenchymal destruction (emphysema).
COPD can be classified into 4 stages based on post-bronchodilator FEV1. Spirometry is essential for diagnosis and provides a description of the severity of pathologic changes in COPD.

COPD is the 4th leading cause of death in the United States and is projected to be the 3rd leading cause of death worldwide by 2020. It is estimated that 4-6% of adult white males and 1-3% of adult white females have COPD. These are probably underestimates as COPD is usually not diagnosed until clinically apparent and often advanced.
The economic and social burden of COPD is high. COPD expenditures for health care costs were estimated at $37.2 billion in 2004.
Because of these factors the Global Initiative for Chronic Obstructive Lung Disease has developed a program to improve the knowledge of epidemiology, socioeconomics, public health and health education of COPD (http://goldcopd.com).
The recommendations made in this CME module are based on recommendations of the GOLD Initiative[1] and a joint statement of the American Thoracic Society/European Respiratory Society.[2]
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